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Topology optimization of piezoelectric bi-material actuators with velocity feedback control

Mariana MORETTI, Emílio C. N. SILVA

Frontiers of Mechanical Engineering 2019, Volume 14, Issue 2,   Pages 190-200 doi: 10.1007/s11465-019-0537-y

Abstract: The bi-material and multifunctional concepts are considered for the design of a controlled piezoelectricThe bi-material piezoelectric actuator (BPEA) has its metallic host layer designed by the TOM, which

Keywords： optimization method     bi-material piezoactuator     active velocity feedback control     time-domain transient analysis     hoststructure design     vibration suppression    

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Lightweight design of an electric bus body structure with analytical target cascading

Frontiers of Mechanical Engineering 2023, Volume 18, Issue 1, doi: 10.1007/s11465-022-0718-y

Abstract: In this study, a lightweight design of a newly developed multi-material electric bus body structure isBy proposing an ATC-based two-level optimization strategy, the original lightweight design problem issubsystem-level optimization model is related to the sub-structural performance objective with sub-structureCompared with the initial design, the total mass is reduced by 49 kg, and the torsional stiffness isIn addition, the obtained design is also validated through strength analysis.

Keywords： electric vehicle     body in white (BIW)     lightweight     analytical target cascading (ATC)    

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Design and applications of morphing aircraft and their structures

Frontiers of Mechanical Engineering 2023, Volume 18, Issue 3, doi: 10.1007/s11465-023-0750-6

Abstract: The design and fabrication of high-performance, lightweight, and intelligent morphing structures havebecome a hot topic in advanced aircraft design.discusses multiple challenges, including flexible structures, flexible skins, and control systems, in the design

Keywords： morphing aircraft     additive manufacturing     lattice structure     smart material     flexible structure     flexible    

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Gene and protein expression of proteinase-activated receptor-1, 2 in a murine model of acute graft host

Quan LI MD , Weiming LI MD , Ping ZOU MD , Jian ZHANG BM ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 309-315 doi: 10.1007/s11684-009-0043-4

Abstract: However, little is known about the function of PAR-1, 2 in acute graft host disease (GVHD).

Keywords： graft vs host disease     proteinase-activated receptor     murine model     hematopoietic stem cell transplantation    

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Integrated analysis of gut microbiome and host immune responses in COVID-19

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 263-275 doi: 10.1007/s11684-022-0921-6

Abstract: Emerging evidence indicates that the gut microbiome contributes to the host immune response to infectiousHere, to explore the role of the gut microbiome in the host immune responses in COVID-19, we conductedWe further analyzed the correlation between the abundance of gut microbes and host responses, and obtainedhighlighted a potential regulatory role of severity related gut microbes in the immune response of host

Keywords： COVID-19     SARS-COV-2     gut microbiome     immune response    

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Optimal dome design considering member-related design constraints

Tugrul TALASLIOGLU

Frontiers of Structural and Civil Engineering 2019, Volume 13, Issue 5,   Pages 1150-1170 doi: 10.1007/s11709-019-0543-5

Abstract: This study proposes to optimize the design of geometrically nonlinear dome structures.analysis with the provisions of American Petroleum Institute specification is employed to optimize the designMoreover, the inclusion of shape-related design variables leads to a decrease in both the weights ofHowever, the designer easily determines the most requested optimal design through the archiving featureConsequently, PAGA is recommended as an optimization tool for the design optimization of geometrically

Keywords： dome structure     geometric nonlinearity     multi-objective optimization     API RP2A-LRFD    

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Development of lunar regolith composite and structure via laser-assisted sintering

Frontiers of Mechanical Engineering doi: 10.1007/s11465-021-0662-2

Abstract: optimized in an appropriate range through orthogonal experiments to establish the relationship of process–structure–propertyproperties of laser-sintered lunar regolith composites are implemented to the topology optimization designand the feasibility of this laser-assisted process are potentially developed for future lightweight design

Keywords： in situ manufacturing     laser-assisted powder fusion process     mechanical properties     topological structuredesign    

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Graft versus host disease after liver transplantation: A case report

Peng-Ji GAO, Xi-Sheng LENG, Dong WANG, Guang-Ming LI, Lei HUANG, Jie GAO, JI-Ye ZHU,

Frontiers of Medicine 2010, Volume 4, Issue 4,   Pages 469-472 doi: 10.1007/s11684-010-0120-8

Abstract: In documenting clinical experience in the diagnosis and treatment of graft host disease (GVHD), we retrospectively

Keywords： liver transplantation     graft versus host disease    

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INTERFERENCE BY NON-HOST PLANT ROOTS AND ROOT EXUDATES IN THE INFECTION PROCESSES OF PHYTOPHTHORA NICOTIANAE

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 3,   Pages 447-459 doi: 10.15302/J-FASE-2021399

Abstract: The interactions between non-host roots and pathogens may be key in the inhibition of soilborne pathogensThese interspecific interactions between non-host roots and pathogens were found to be an important factor

Keywords： fennel and tobacco rotation     infection behavior     Phytophthora nicotianae     reactive oxygen species     vanillin    

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A dream of flotation reagents—study on relationship between structure and property of flotation reagentsand molecular design

Wang Dianzuo,Yao Guocheng

Strategic Study of CAE 2011, Volume 13, Issue 3,   Pages 4-11

Abstract: The paper introduced the relationship between structure and property of flotation reagents, and discussedthe hisftory and new progress on molecular design of flotation reagents.

Keywords： mineral processing     flotation reagents     structure and property     molecular design    

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Supporting structure form and parameters design of Bohai Strait tunnel

Wan Fei,Wang Yunlong,Wu Yongsheng

Strategic Study of CAE 2013, Volume 15, Issue 12,   Pages 61-66

Abstract: experience of subsea tunnels having been completed,the engineering analogy method can be adopted to designsupporting structure form and parameters of Bohai Strait tunnel.the surrounding rock,corresponding combination supporting measures are adopted in the primary support designIn the stress analysis of lining structure, safety coefficients under different water pressure are analyzed,and the design parameters of secondary lining are preliminarily determined.

Keywords： Bohai Strait     subsea tunnel     structure form     design parameters    

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Permeability and thermal conductivity of host compressed natural graphite for consolidated activated

Bo TIAN, Liwei WANG, Zhequan JIN, Ruzhu WANG

Frontiers in Energy 2011, Volume 5, Issue 2,   Pages 159-165 doi: 10.1007/s11708-011-0145-y

Abstract: thermal conductivity test units were set up to study the heat and mass transfer performance of the hostSuch a result showed that CENG was a promising host material for AC to improve the heat transfer performance

Keywords： permeability     thermal conductivity     expanded nature graphite     activated carbon    

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DISCOVERY OF TRIKETONE-QUINOXALINE HYBRIDS AS POTENT HPPD INHIBITORS USING STRUCTURE-BASED DRUG DESIGN

Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 1,   Pages 133-145 doi: 10.15302/J-FASE-2021401

Abstract: A battery of novel triketone-quinoxaline compounds has been designed using a structure-based drug designdiscovering HPPD inhibitors with substantially increased potency, providing insight into the molecular design

Keywords： herbicide / HPPD / inhibitor / quinoxaline / triketon    

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Consistency Guarantees for Professional Appraisal of Geotechnical Engineering Design under Market Leading

Jian-ye Zheng

Frontiers of Engineering Management 2015, Volume 2, Issue 1,   Pages 82-85 doi: 10.15302/J-FEM-2015012

Abstract: Clients refer to reviewers as referees since they help to determine the fate of a design.In an open peer review refereeing a retaining and protection structure design of building foundation

Keywords： peer review     foundation pit excavation     retaining and protection structure     design introduction    

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Host protection against Omicron BA.2.2 sublineages by prior vaccination in spring 2022 COVID-19 outbreak

Frontiers of Medicine 2023, Volume 17, Issue 3,   Pages 562-575 doi: 10.1007/s11684-022-0977-3

Abstract: The Omicron family of SARS-CoV-2 variants are currently driving the COVID-19 pandemic. Here we analyzed the clinical laboratory test results of 9911 Omicron BA.2.2 sublineages-infected symptomatic patients without earlier infection histories during a SARS-CoV-2 outbreak in Shanghai in spring 2022. Compared to an earlier patient cohort infected by SARS-CoV-2 prototype strains in 2020, BA.2.2 infection led to distinct fluctuations of pathophysiological markers in the peripheral blood. In particular, severe/critical cases of COVID-19 post BA.2.2 infection were associated with less pro-inflammatory macrophage activation and stronger interferon alpha response in the bronchoalveolar microenvironment. Importantly, the abnormal biomarkers were significantly subdued in individuals who had been immunized by 2 or 3 doses of SARS-CoV-2 prototype-inactivated vaccines, supporting the estimation of an overall 96.02% of protection rate against severe/critical disease in the 4854 cases in our BA.2.2 patient cohort with traceable vaccination records. Furthermore, even though age was a critical risk factor of the severity of COVID-19 post BA.2.2 infection, vaccination-elicited protection against severe/critical COVID-19 reached 90.15% in patients aged ≥ 60 years old. Together, our study delineates the pathophysiological features of Omicron BA.2.2 sublineages and demonstrates significant protection conferred by prior prototype-based inactivated vaccines.

Keywords： SARS-CoV-2     COVID-19     host response     bronchoalveolar lavage fluid (BALF)    

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Title Author Date Type Operation

Topology optimization of piezoelectric bi-material actuators with velocity feedback control

Mariana MORETTI, Emílio C. N. SILVA

Journal Article

Lightweight design of an electric bus body structure with analytical target cascading

Journal Article

Design and applications of morphing aircraft and their structures

Journal Article

Gene and protein expression of proteinase-activated receptor-1, 2 in a murine model of acute graft host

Quan LI MD , Weiming LI MD , Ping ZOU MD , Jian ZHANG BM ,

Journal Article

Integrated analysis of gut microbiome and host immune responses in COVID-19

Journal Article

Optimal dome design considering member-related design constraints

Tugrul TALASLIOGLU

Journal Article

Development of lunar regolith composite and structure via laser-assisted sintering

Journal Article

Graft versus host disease after liver transplantation: A case report

Peng-Ji GAO, Xi-Sheng LENG, Dong WANG, Guang-Ming LI, Lei HUANG, Jie GAO, JI-Ye ZHU,

Journal Article

INTERFERENCE BY NON-HOST PLANT ROOTS AND ROOT EXUDATES IN THE INFECTION PROCESSES OF PHYTOPHTHORA NICOTIANAE

Journal Article

A dream of flotation reagents—study on relationship between structure and property of flotation reagentsand molecular design

Wang Dianzuo,Yao Guocheng

Journal Article

Supporting structure form and parameters design of Bohai Strait tunnel

Wan Fei,Wang Yunlong,Wu Yongsheng

Journal Article

Permeability and thermal conductivity of host compressed natural graphite for consolidated activated

Bo TIAN, Liwei WANG, Zhequan JIN, Ruzhu WANG

Journal Article

DISCOVERY OF TRIKETONE-QUINOXALINE HYBRIDS AS POTENT HPPD INHIBITORS USING STRUCTURE-BASED DRUG DESIGN

Journal Article

Consistency Guarantees for Professional Appraisal of Geotechnical Engineering Design under Market Leading

Jian-ye Zheng

Journal Article

Host protection against Omicron BA.2.2 sublineages by prior vaccination in spring 2022 COVID-19 outbreak

Journal Article